Research Grants
Grant #52
Melissa Wasserstein, MD
Children’s Hospital at Montefiore, New York
PROJECT TITLE: Niemann-Pick disease: Genotype/Phenotype Analyses and Molecular Based Therapy
PROJECT DATES: October 2014 – October 2018
PROJECT STATUS: In Progress
PROJECT LAY SUMMARIES:
- December 2019
- June 2019
- December 2018
- October 2018
- December 2017
- August 2016
- October 2015
- April 2015
- October 2014
$100,000
Funded by the NNPDF
Grant #51
Charles Vite, DVM, PhD
School of Veterinary Medicine, University of Pennsylvania – Philadelphia
PROJECT TITLE: NPC Cat Colony “Fellowships of the Cats II”
PROJECT DATES: August 2013 – July 2015
PROJECT STATUS: Complete
PROJECT LAY SUMMARIES:
2013 Family Conference Presentation (PDF)
$100,000
Jointly Funded by the NNPDF & CCNNPDF
Extended additional two months
Grant #50
Charles Vite, DVM, PhD
School of Veterinary Medicine, University of Pennsylvania – Philadelphia
PROJECT TITLE: NPC Cat Colony “Fellowships of the Cats I”
PROJECT DATES: August 2011 – September 2013
PROJECT STATUS: Complete
PROJECT LAY SUMMARIES:
2012 ARTICLE: Cyclodextrin Therapy in the NPC cat model
$100,000
Jointly Funded by the NNPDF & CCNNPDF
Grant #49
Jackson Laboratory Repository
PROJECT TITLE: Processing the NPD Mouse Model Developed by Dr. Richard Pagano of the Mayo Clinic College of Medicine
PROJECT DATES: August 2009
PROJECT STATUS: Complete
$2,500
Jointly Funded by the NNPDF & CCNNPDF
Grant #48
Edward H. Schuchman, PhD
PROJECT TITLE: Construction & Characterization of New Mouse Models for Types A & B Niemann-Pick
PROJECT DATES: April 2008 – March 2009
PROJECT STATUS: Complete
PROJECT LAY SUMMARIES:
$46,593
Jointly Funded by the NNPDF & CCNNPDF
Grant #47
Frances M. Platt, PhD & Emyr Lloyd-Evans, PhD
University of Oxford, Oxford, UK (2 years)
PROJECT TITLE: Targeting Sphingosine Storage as a New Therapeutic approach for Niemann-Pick Type C
PROJECT DATES: March 2008 – February 2010
PROJECT STATUS: Complete
PROJECT LAY SUMMARIES:
$161,097
Jointly Funded by the NNPDF & CCNNPDF
Grant #46
Lysosomal Storage Disease Research Consortium
(Multiple / 1 year)
PROJECT TITLE: Additional Contribution to Lysosomal Storage Disease (LSD) Research Consortium for Research Into Issues of Common Interest to all LSD Support Groups
Also See Grant #40
PROJECT DATES: April 2007 – March 2008
PROJECT STATUS: Complete
$10,000
Jointly Funded by the NNPDF & CCNNPDF
Grant #45
Frances M. Platt, PhD
University of Oxford, Oxford, UK (1 year)
PROJECT TITLE: Evaluation of Anti-Inflammatory Intervention (NSAIDS) as an Adjunctive Therapy in Niemann-Pick Type C1 Disease
PROJECT DATES: March 2007 – February 2008
PROJECT STATUS: Complete
PROJECT SUMMARY:
$99,090
Jointly Funded by the NNPDF & CCNNPDF
Grant #44
Lysosomal Storage Disease Research Consortium
(Multiple / 1 year)
PROJECT TITLE: Additional Contribution to Lysosomal Storage Disease (LSD) Research Consortium for Research Into Issues of Common Interest to all LSD Support Groups
Also See Grant #40
PROJECT DATES: April 2006 – March 2007
PROJECT STATUS: Complete
$10,000
Jointly Funded by the NNPDF & CCNNPDF
Grant #43
Maria D. Ledesma, PhD
Catholic University of Leuven, Leuven, Belgium (1 Year)
PROJECT TITLE: Analysis of Dendritic Spine Alterations in Niemann-Pick disease Type A Neurons
PROJECT DATES: September 2006 – August 2007
PROJECT STATUS: Complete
PROJECT SUMMARY:
2014 ASMD Research Publication
$19,760
Bridge Funding
Jointly Funded by the NNPDF & CCNNPDF
Grant #42
Kostantin Dobrenis, PhD
Albert Einstein College of Medicine of Yeshiva University, Bronx, NY USA (18 Months)
PROJECT TITLE: Establishment of Central Nervous System Cell Lines from NPC-1 Disease Mice for Pathogenic and Therapeutic Studies
PROJECT DATES: June 2006 – December 2007
PROJECT STATUS: Complete
PROJECT SUMMARY:
$80,240
Jointly Funded by the NNPDF & CCNNPDF
Grant #41
Frances M. Platt, PhD
University of Oxford, Oxford, UK
PROJECT TITLE: Therapeutic Monitoring of Glycolipid Storage Diseases in the Clinic Using Cell Biological Assays and Proteomics
PROJECT DATES: May 2006 – November 2006
PROJECT STATUS: Complete
PROJECT SUMMARY:
$50,000
Bridge Funding
Jointly Funded by the NNPDF & CCNNPDF
Grant #40
Lysosomal Storage Disease Research Consortium
(Multiple)
PROJECT TITLE: Lysosomal Storage Disease Research Consortium Contribution for NNPDF to Join Consortium
PROJECT DATES: April 2004 – March 2006
PROJECT STATUS: Complete
$10,000
Jointly Funded by the NNPDF & CCNNPDF