“Pfrieger’s Digest” is written by Frank Pfrieger of Niemann-Pick Selbsthiifegruppe (Germany) to provide an overview of the latest advances in Niemann-Pick disease based on recent scientific publications.
Frank Pfrieger is group leader at the Institute of Cellular and Integrative Neurosciences in Strasbourg (France), which is part of the French Centre National de la Recherche Scientifique (CNRS) and affiliated with the University of Strasbourg. His research focuses on cholesterol metabolism in the brain and the mechanisms of neurodegeneration in Niemann-Pick type C disease.
Frank entered the field of Niemann-Pick type C disease 17 years ago. His previous research had raised fundamental questions about how cells in the brain meet their need for cholesterol, and defects in NPC1 appeared as a good model to test our hypotheses. Over time, he met patients, their parents and friends, and he realized the need to explain what research is all about, why it takes so long and what it takes to make progress. For several years, Frank wrote conference reports for the German NPC association. Beginning of 2020, he created “Pfrieger’s Digest”, a sort of “magazine” that informs non-specialists about the latest advances in the field based on scientific publications.